Microbiome

At GC Genome, we recognize the significance of
the microbiome to unlocking its mysteries.

The Microbiome’s Impact on Health and Wellness

The microbiome is a crucial ecosystem of microorganisms that live in and on our bodies.
It plays a vital role in various aspects of our health, including digestion, immune function,
and even mental well-being.
Understanding and harnessing the power of the microbiome has the potential to revolutionize
healthcare and improve overall human well-being.

Considerations for Successful Microbiome Study

A microbiome study consists of three phases: design, experiment, and statistics. Decisions on each phase significantly affect the final results of the study.

The experiment exerts the most significant effect on microbiome study findings than study design and statistics. Microbiome studies are typically performed using 16S rRNA amplicon sequencing method. The results are represented as the composition and proportion of the microbiome in each sample.

The findings of 16S amplicon sequencing microbiome experiment can be affected by various processes from sampling, transportation, DNA extraction, PCR, sequencing, and BI analysis. A change to even one of these processes may significantly change the experiment results regarding the existence or proportion of microorganisms detected.

Government Research Project

GC Genome’s new HRD(transcriptional HRD) test can more accurately detect patients who are responsive to drugs compared to the existing DNA-based HRD testing method. Our approach focused on a novel but widespread transcriptional mechanism by which HRD arises independently of BRCA1/2 mutations. This test can serve as a companion diagnostic for PARP inhibitors, providing valuable guidance in treatment decisions.

Our Publication on Frontiers in Genetics

The association between gut microbiome and
hypertension varies according to enterotypes:
a Korean study

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Knowing all about microbiomes in your body
and getting personalized health guideline

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Focused Areas: Liquid Biopsy

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